Antibacterial Activity of Copper and Cobalt Amino Acids Complexes

  • ANDREEA STĂNILĂ University of Agricultural Science and Veterinary Medicine, 3-5 Manastur Street, 400372, Cluj-Napoca,
  • Cornelia BRAICU The Oncology Institute “Prof. Dr. Ion Chiricuţă”, 34-36 Republicii Street, 400015, Cluj-Napoca
  • Sorin STĂNILĂ University of Agricultural Science and Veterinary Medicine, 3-5 Manastur Street, 400372, Cluj-Napoca,
  • Raluca M. POP University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, 3-5 Manastur St., 400372

Abstract

The antibacterial properties of differently copper and cobalt amino acids complexes on agar plates was investigated in the present study. The antibacterial activity of amino acid complexes was evaluated against on three bacteria strains (Escherichia coli, Bacillus cereus, Micrococcus luteus). Generally, the amino acids complexes were mainly active against gram-positive organisms, species like Micrococcus luteus being the most susceptible strain tested. It was registered a moderate antibacterial activity against Bacillus cereus. The microorganisms Escherichia coli, which are already known to be multi-resistant to drugs, were also resistant to the amino acids complexes but also to the free salts tested. Escherichia coli were susceptible only to the CoCl2 and copper complex with phenylalanine. The complexes with leucine and histidine seem to be more active than the parent free ligand against one or more bacterial species. Moderate activity was registered in the case of complexes with methionine and phenylalanine. From the complexes tested less efficient antibacterial activity was noted in the case of complexes with lysine and valine. These results show that cobalt and copper complexes have an antibacterial activity and suggest their potential application as antibacterial agents.

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Author Biography

ANDREEA STĂNILĂ, University of Agricultural Science and Veterinary Medicine, 3-5 Manastur Street, 400372, Cluj-Napoca,
USAMV Cluj-Napoca Faculty of Agriculture
Published
2011-11-21
How to Cite
STĂNILĂ, A., BRAICU, C., STĂNILĂ, S., & POP, R. M. (2011). Antibacterial Activity of Copper and Cobalt Amino Acids Complexes. Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 39(2), 124-129. https://doi.org/10.15835/nbha3926847
Section
Research Articles