The role of medicinal mushrooms as gastroprotective agents: A short narrative review


  • Aida PUIA University of Medicine and Pharmacy Iuliu Hatieganu, Department of Community Medicine, Cluj-Napoca (RO)
  • Diana SCHLANGER University of Medicine and Pharmacy Iuliu Hatieganu, Department of Surgery, Cluj-Napoca (RO)
  • Ion C. PUIA University of Medicine and Pharmacy Iuliu Hatieganu, Department of Surgery, Cluj-Napoca; Regional Institute of Gastroenterology and Hepatology "Octavian Fodor, Surgery Department, Cluj-Napoca (RO)



gastro protectants, stomach ulcers, therapeutic mushrooms


This review examines the possible clinical uses of extracts from mushrooms with medicinal properties, particularly their role as gastroprotective agents. After conducting a thorough examination of the literature, we identified and chose publications that presented six distinct types of mushroom extracts. These extracts have been experimentally demonstrated to have gastroprotective effects in animal models. Animals like rats or mice were used as subjects in experimental models to generate stomach ulcers through various approaches, such as chemical induction or inducing stress. Studies have shown that mushroom extracts are efficacious in facilitating the healing process of stomach ulcers. Several fundamental modes of action include anti-inflammatory and antioxidant effects, along with enhanced preservation of stomach mucus. No clinical trials pertaining to this topic have been uncovered. However, the initial positive outcomes gained serve as a basis for additional investigation on this subject.


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How to Cite

PUIA, A., SCHLANGER, D., & PUIA, I. C. (2023). The role of medicinal mushrooms as gastroprotective agents: A short narrative review. Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 51(4), 13532.



Review Articles
DOI: 10.15835/nbha51413532

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