Assessment of cold stress tolerance in maize through quantitative trait locus, genome-wide association study and transcriptome analysis

  • Syed F.A. GILLANI Gansu Agricultural University, College of Agronomy, Lanzhou 730070 (CN)
  • Adnan RASHEED Jilin Changfa Modern Agricultural Science and Technology Group Co., Ltd. (CN)
  • Gai YUHONG Jilin Agricultural University, College of Agronomy (CN)
  • Wei JIAN Jilin Changfa Modern Agricultural Science and Technology Group Co., Ltd. (CN)
  • Wang Y. XIA Gansu Agricultural University, College of Agronomy, Lanzhou 730070;Gansu Provincial Key Lab of Arid Land Crop Science, Lanzhou 730070 (CN)
  • Huma TARIQ University of Poonch Rawalakot Azad Kashmir, Laboratory of Plant Breeding and Molecular Genetic (CN)
  • Muhammad ILYAS University of Poonch Rawalakot Azad Kashmir, Laboratory of Plant Breeding and Molecular Genetic (PK)
  • Peng YUNLING Gansu Agricultural University, College of Agronomy, Lanzhou 730070;Gansu Provincial Key Lab of Arid Land Crop Science, Lanzhou 730070 (CN)
Keywords: GWAS, functional genomics, mixed model, population design, Zea mays


Genome-wide association study (GWAS) has become a widely accepted strategy for decoding genotype phenotype associations in many species thanks to advances in next-generation sequencing (NGS) technologies. Maize is an ideal crop for GWAS and significant progress has been made in the last decade. This review summarizes current GWAS efforts in maize functional genomics research and discusses future prospects in the omics era. The general goal of GWAS is to link genotypic variations to corresponding differences in phenotype using the most appropriate statistical model in a given population. The current review also presents perspectives for optimizing GWAS design and analysis. GWAS analysis of data from RNA, protein, and metabolite-based omics studies is discussed, along with new models and new population designs that will identify causes of phenotypic variation that have been hidden to date. The detailed that low temperature in maize seedlings altogether restricts germination and seedlings' development and destabilizes the cancer prevention agent safeguard component. Cold pressure adversely influences root morphology, photosystem II (PS II) effectiveness, chlorophyll substance, and leaf region. A short scene of low temperature stress (for example, under 10 °C for 7 days) during the V6–V9 maize development stages can fundamentally defer the anthesis commencement. Among the morphological reactions by focused on maize plants, low temperature stress causes strange tuft development in maize, along these lines influencing the fertilization and grain filling measures. Hence, problematic temperatures can cause a genuine yield decrease if happening at basic conceptive stages, as plants allocate over half of their photosynthesis to foster grains during this stage until physiological development. Low temperature stress fundamentally diminishes the plant stature and absolute yield biomass of maize. Leaf improvement turns out to be delayed in chilly focused on plants because of a drawn-out cell cycle and diminished pace of mitosis.  The joint and continuous efforts of the whole community will enhance our understanding of maize quantitative traits and boost crop molecular breeding designs.


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GILLANI, S. F., RASHEED, A., YUHONG, G., JIAN, W., XIA, W. Y., TARIQ, H., ILYAS, M., & YUNLING, P. (2021). Assessment of cold stress tolerance in maize through quantitative trait locus, genome-wide association study and transcriptome analysis. Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 49(4), 12525.
Review Articles
DOI: 10.15835/nbha49412525

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