Characterization of Trametes versicolor: Medicinal Mushroom with Important Health Benefits

Raluca M. POP, Ion Cosmin PUIA, Aida PUIA, Veronica S. CHEDEA, Nicolae LEOPOLD, Ioana C. BOCSAN, Anca D. BUZOIANU

Abstract


Trametes species represents a rich source of nutritive compounds with important pharmacological properties like antioxidant, antiinflammatory and anti-cancer properties. However, factors like genetic background, harvesting period, geographic location, climatic conditions and others are influencing the biosynthesis of bioactive compounds, their fingerprint and their concentration. The aim of this study was to determine the antioxidant capacity, total phenolic compounds and total flavonoids content of two mushroom species, namely Tramestes versicolor (TV) and Trametes gibbosa (TG), mushrooms with potential health benefits, harvested from north-west part of Romania. In order to determine the phenolic compounds profile, water, methanol, and acetone mushroom extracts were analyzed using UV-Vis spectroscopy, FTIR spectroscopy and LC-MS analysis. In total 28 compounds were tentatively identified as phenolic acids (11 compounds), flavonols (6 compounds), flavones (6 compounds), coumarins (2 compounds), flavanols, isoflavonoids and biflavonoids (1 compound). The highest antioxidant activity was determined for the methanolic extract while the highest total polyphenols content and total flavonoids content were determined for the water extract. The results obtained suggested that Trametes species can be considered important sources of bioactive compounds, their phenolics composition and content being influenced by a series of factors like geographic area origin and genetic background.


Keywords


chromatography; flavonoids; FTIR spectroscopy; mass spectrometry; phenolics; polypore mushroom

Full Text:

PDF

References


Abugri DA, Mcelhenney WH (2013). Extraction of Total Phenolic and Flavonoids from Edible Wild and Cultivated Medicinal Mushrooms as Affected by Different Solvents. Journal of Natural Products and Plant Resources 3:37-42.

Alispahic A, Salihovic M, Ramic E, Pazalja A (2015). Phenolic content and antioxidant activity of mushroom extracts from Bosnian market. Bulletin of the Chemists and Technologists of Bosnia and Herzegovina 44:5-8.

Balmus IM, Ciobica A, Antioch I, Dobrin R, Timofte D (2016). Oxidative Stress Implications in the Affective Disorders: Main Biomarkers, Animal Models Relevance, Genetic Perspectives, and Antioxidant Approaches. Oxidative Medicine and Cellular Longevity 2016:1-25.

Barros L, Ferreira M-J, Queirós B, Ferreira ICFR, Baptista P (2007). Total phenols, ascorbic acid, ?-carotene and lycopene in Portuguese wild edible mushrooms and their antioxidant activities. Food Chemistry 103:413-419.

Brand-Williams W, Cuvelier ME, Berset C (1995). Use of a free radical method to evaluate antioxidant activity. LWT - Food Science and Technology 28:25-30.

Cheung L, Cheung P (2005) Mushroom extracts with antioxidant activity against lipid peroxidation. Food Chemistry 89:403-409.

Cruz A, Pimentel L, Rodríguez-Alcalá LM, Fernandes T, Pintado M (2016). Health benefits of edible mushrooms focused on Coriolus versicolor: A review. Journal of Food and Nutrition Research 4:773-781.

Cui J, Chisti Y (2003). Polysaccharopeptides of Coriolus versicolor: physiological activity, uses, and production. Biotechnology Advances 21:109-122.

Dulf FV, Vodnar DC, Dulf E-H, Pintea A (2017). Phenolic compounds, flavonoids, lipids and antioxidant potential of apricot (Prunus armeniaca L.) pomace fermented by two filamentous fungal strains in solid state system. Chemistry Central Journal 11:92.

Ferreira IC, Vaz JA, Vasconcelos MH, Martins A (2010). Compounds from wild mushrooms with antitumor potential. Anticancer Agents in Medicinal Chemistry 10:424-36.

Flamini R (2013). Recent applications of mass spectrometry in the study of grape and wine polyphenols. ISRN Spectroscopy 2013:45.

Janjuševic L, Karaman M, Šibul F, Tommonaro G, Iodice C, Jakovljevic D, Pejin B (2017). The lignicolous fungus Trametes versicolor (L.) Lloyd (1920): a promising natural source of antiradical and AChE inhibitory agents. Journal of Enzyme Inhibition and Medicinal Chemistry 32:355-362.

Kamiyama M, Horiuchi M, Umano K, Kondo K, Otsuka Y, Shibamoto T (2013). Antioxidant/anti-inflammatory activities and chemical composition of extracts from the mushroom Trametes versicolor. International Journal of Nutrition and Food Sciences 2:85-91.

Li F, Wen H, Zhang Y, Aa M, Liu X (2011). Purification and characterization of a novel immunomodulatory protein from the medicinal mushroom Trametes versicolor. Science China Life Sciences 54:379-385.

Masek A, Chrzescijanska E, Kosmalska A, Zaborski M (2014). Characteristics of compounds in hops using cyclic voltammetry, UV-VIS, FTIR and GC-MS analysis. Food Chemistry 156:353-361.

Ng TB (1998). A review of research on the protein-bound polysaccharide (polysaccharopeptide, PSP) from the mushroom Coriolus versicolor (basidiomycetes: Polyporaceae). General Pharmacology: The Vascular System 30:1-4.

Nickless EM, Holroyd SE, Stephens JM, Gordon KC, Wargent JJ (2014). Analytical FT-Raman spectroscopy to chemotype Leptospermum scoparium and generate predictive models for screening for dihydroxyacetone levels in floral nectar. Journal of Raman Spectroscopy 45:890-894.

Özgör E, Meltem U, Irem C, Semiha SY, Nevin K (2016). Investigation of antimicrobial activity of different Trametes versicolor extracts on some clinical isolates. Biological Chemistry 43:267-272.

Plazonic A, Bucar F, Males Z, Mornar A, Nigovic B, Kujundzic N (2009). Identification and Quantification of Flavonoids and Phenolic Acids in Burr Parsley (Caucalis platycarpos L.), using High-Performance Liquid Chromatography with Diode Array Detection and Electrospray Ionization Mass Spectrometry. Molecules 14:2466-2490.

Pop RM, Socaciu C, Pintea A, Buzoianu AD, Sanders MG, Gruppen H, Vincken J-P (2013). UHPLC/PDA-ESI/MS analysis of the main berry and leaf flavonol glycosides from different Carpathian Hippophaë rhamnoides L. varieties. Phytochemical Analysis 24:484-492.

Preserova J, Ranc V, Milde D, Kubistova V, Stavek J (2015). Study of phenolic profile and antioxidant activity in selected Moravian wines during winemaking process by FT-IR spectroscopy. Journal of Food Science and Technology 52:6405-6414.

Puttaraju NG, Venkateshaiah SU, Dharmesh SM, Urs SMN, Somasundaram R (2006). Antioxidant activity of indigenous edible mushrooms. Journal of Agricultural and Food Chemistry 54:9764–9772.

Shokrzadeh M, Azdo S, ahmadi MA, Habibi E (2017). Anti-diabetic effect of methanol extract of Trametes versicolor on male mice. Journal of Mazandaran University of Medical Sciences 26:165-175.

Standish LJ, Wenner CA, Sweet ES, Bridge C, Nelson, A, Martzen M, Torkelson C (2008). Trametes versicolor mushroom immune therapy in breast cancer. Journal of the Society for Integrative Oncology 6:122-128.

Tahir HE, Xiaobo Z, Zhihua L, Jiyong S, Zhai X, Wang S, Mariod AA (2017). Rapid prediction of phenolic compounds and antioxidant activity of Sudanese honey using Raman and Fourier transform infrared (FT-IR) spectroscopy. Food Chemistry 226:202-211.

Teplyakova TV, Psurtseva NV, Kosogova TA, Mazurkova NA, Khanin VA, Vlasenko VA (2012). Antiviral activity of polyporoid mushrooms (higher Basidiomycetes) from Altai Mountains (Russia). International Journal of Medicinal Mushrooms 14:37-45.

Uttara B, Singh A V., Zamboni P, Mahajan RT (2009.) Oxidative stress and neurodegenerative diseases: A review of upstream and downstream antioxidant therapeutic options. Current Neuropharmacology 7:65-74.

Vamanu E, Voica A (2017). Total phenolic analysis, antimicrobial and antioxidant activity of some mushroom tinctures from medicinal and edible species, by in vitro and in vivo tests. Scientific Bulletin. Series F. Biotechnologies 21:318-324.

Yahia EM, Gutiérrez-Orozco F, Moreno-Pérez MA (2017). Identification of phenolic compounds by liquid chromatography-mass spectrometry in seventeen species of wild mushrooms in Central Mexico and determination of their antioxidant activity and bioactive compounds. Food Chemistry 226:14-22.

Zhu M, Dong X, Guo M, Ferreira I, McPhee DJ (2015). Phenolic profiling of Duchesnea indica combining macroporous resin chromatography (MRC) with HPLC-ESI-MS/MS and ESI-IT-MS. Molecules 20:22463-22475.

Zhuo-Teng Y, Bo L, Purna M, Newburg DS (2013). Trametes versicolor extract modifies human fecal microbiota composition in vitro. Plant Foods for Human Nutrition 68:107-112.




DOI: http://dx.doi.org/10.15835/nbha46211132

June 1, 2018: Notulae Botanicae Horti Agrobotanici Cluj-Napoca in Scopus – Elsevier CiteScore 2017=0.78, Horticulture; Agronomy and Crop Science; Plant Science


 
http://not-bot-horti-agrobo.blogspot.com/
https://www.facebook.com/NotBotHA
https://twitter.com/NotBotHA